Rosetta vs other protein folding projects

Message boards : Cafe Rosetta : Rosetta vs other protein folding projects

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David Canning

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Message 21 - Posted: 17 Sep 2005, 0:07:03 UTC

How does Rosetta@home differ from Folding@Home and the World Community grid's human proteome project?
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Message 24 - Posted: 17 Sep 2005, 0:19:26 UTC - in response to Message 21.  
Last modified: 17 Sep 2005, 0:38:24 UTC

How does Rosetta@home differ from Folding@Home and the World Community grid's human proteome project?


Folding@home studies the process of folding using molecular dynamics. Distributed computing is allowing them to do simulations at time scales (milliseconds) that are not possible without thousands of computers. We, on the other hand, are doing protein fold predictions and design, including protein complexes. The WCG project is applying our Rosetta software to the human genome and other genomes, in collaboration with our group. We are trying to improve the software (focusing on research, development, and testing).
For example, what we learn through our project may help the WCG in their next phase for high-resolution structure prediction.
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Message boards : Cafe Rosetta : Rosetta vs other protein folding projects



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